520/580.495 

Microfabrication Laboratory

This laboratory course is an introduction to the principles of microfabrication for microelectronics, sensors, MEMS, and other synthetic microsystems that have applications in medicine and biology. Course comprises of laboratory work and accompanying lectures that cover silicon oxidation, aluminum evaporation, photoresist deposition, photolithography, plating, etching, packaging, design and analysis CAD tools, and foundry services. This year's class project  is an active DNA microchip array.

Fall 2000

Staff

Professor Andreas G. Andreou, Latrobe 229, 410-516-8361,
 
Jennifer Blain, (Teaching Assistant) Latrobe 226, 410-516-0258, blain@jhu.edu
 
Francisco Tejada (Laboratory Assistant) Latrobe 226, 410-516-0258 ft1@jhu.edu

Course Logistics

Course Ethics

Homework and pre-laboratory assignments: In a laboratory course, you have ample opportunities for collaboration. Developing the ability to work well in a group is certainly one of the objectives for this course. However, homework assignments, pre-lab write-ups and examinations must be done on your own. Please read here what you are supposed to do alone and how much you are allowed to collaborate.

Laboratory safety and environment awareness: When working in the lab you must follow all proper procedures to avoid injuring yourself or anyone else that works with you. When disposing chemical waste it is important that you follow proper laboratory procedures to assure that our environment stays clean and free from contaminants. Please read the Laboratory Safety handout, and revisit it periodically to refresh yourself and especially when in doubt about a particular process or procedure. After  reading the Laboratory Safety handout please download, print and sign the pledge to be a good lab citizen and follow all safety rules and regulations. The signed pledge must be handed in with the first homework assignment.

Textbook

Introduction to Microelectronic Fabrication

Richard C. Jaeger

Volume V;  Modular Series on Solid State Devices

G. W. Neudeck and R.F. Pierret eds. Addison-Wesley, 1993.

ISBN 0-201-14695-9

Schedule and Syllabus

Week

Lecture topics

Laboratory session

1

Organizational meeting

 

2

Introduction

DNA microchips and microfabrication

Handout  #1

Tour of laboratory facilities and review of safety procedures on site.

Lab #0 

Laboratory microscope and profilometer.

3

Photolithography (I): Basics (Chapter 2)

Handout  #2

 

Lab #1

CAD tools and mask design

4

Thermal oxidation of silicon (Chapter 3)

Handout  #3

Lab #2

Wafer oxidation.

5

Film deposition (Chapter 6.1, 6.2)

Handout  #4

Lab #3

Aluminum deposition.

6

Photolithography (II): Positive photoresists 

Handout  #5

Lab #4

Photolithography; metal pattern definition and annealing.

7

Wet Etching

Handout  #6

Lab #5

SU8 photoresist deposition and curing; electrode areas/cuts definition and opening.

8

Plating

Handout #7

 

Lab #6

Immersion gold plating.

9

Packaging and testing (Chapter 8)

Handout  #8

Lab #7 (Instructions to be given in the lab)

Wafer dicing, packaging and bonding.

10

CMOS (Chapter 9) and  MEMS design

MOSIS and Cronus  and MEMS Exchange foundries

Handout  #9

Lab #8 (Instructions to be given in the lab)

Device testing and characterization

Individual project  work.

11

Soft-lithography; microfabrication for medicine and biology - a review-

Handout  #10

Thanksgiving 

No laboratory sessions.

12

Project presentation and discussion (I) Lab #9

Individual project  work.

13

Project presentation and discussion (II)

Lab #10

Optional individual project  work.

CAD Tools

The CAD  program LEDIT will be used for mask design.

Homework Assignments and Solutions

Homework #1: Due 9/27/2000 Solutions to Homework #1
Homework # 2: Due 10/4/2000 Solutions to Homework #2
Homework # 3: Due 10/11/1999  Solutions to Homework #3 
Homework # 4: Due 10/18/1999 Solutions to Homework #4
Midterm Exam 

Part (I): Due 9.00 a.m. 11/8/2000

Solutions to Midterm Part (I)
Homework # 5: Due 11/15/2000 Solutions to Homework #5
Homework # 6: Due 11/22/2000 Solutions to Homework #6

Project presentation: 11/29/2000 and 12/6/2000

 

Written project report due: 5.00 p.m. 12/7/2000

Absolutely no extensions!

Reading References:

1. Introduction to Microelectronic Fabrication , Richard C. Jaeger, Volume V;  Modular Series on Solid State Devices , G. W. Neudeck and R.F. Pierret eds., Addison-Wesley, 1993.

2. Silicon as Mechanical Material , K. E. Petersen, Proceedings of  IEEE, vol. 70, no. 5, pp. 420-457, May 1982.

3. Soft Lithography, Younan Xia and George M. Whitesides,  Angewandte Chemie, International Edition, 37, 550-575, 1998.

4. DNA Microarrays: A practical approach, M. Shena editor, The Practical Approach Series, Oxford University Press, Oxford 1999 (reprinted 2000).

5. Nanogen Corporation, Product and technology section, http://www.nanogen.com/tech.htm 

6. Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips, J. Cheng, et.al. Nature Biotechnology, vol. 16, pp. 541-546, June 1998.

 

Frequently Asked Questions about procedures and equipment in the lab.

         How do I …. ? FAQ

Links to Equipment and Supplies

MOSIS links

Printed Circuit Board manufacturing and design software

MICROCHEM Corp (SU-8 photoresist supplier)

SOTEC Microsystems (SU-8 photoresist supplier)

Technic Inc (Plating solutions)

Transene (Etching, Plating, Cleaning solutions)

Small Parts (Tubing, solder and alloys)

Web Pages from Previous Years

1994 Final Project Report by Tim Edwards.

1998 Microfabrication Laboratory WWW page.

1999 Microfabrication Laboratory WWW page.

Links to Microfabrication, Soft Lithography and MEMS

MEMS clearing house at ISI (MOSIS)

Cronus MEMS foundry

MEMS Exchange

U.C. Berkeley MEMS page

MIT MEMS page

University of Michigan microfabrication laboratory

U.C. Davis microfabrication laboratory

Caltech micromachining laboratory

Center for Applied Microtechnology at University of Washington

Whitesides Group at Harvard


Acknowledgements


This course is supported by a Whitaker Foundation Development grant and by Kenan grants from the Whiting School of Engineering. 

To see a layout of our new facility (to be) in the Biomedical Engineering Institute at Homewood campus click here!


Page maintained by A.G. Andreou, andreou@jhu.edu , Last update: Tuesday, August 28, 2007